Category: Aldol Condensation

What is aldol condensation? When aldehydes and ketones having at least one α-hydrogen are treated with dilute alkali (which act as a catalyst) they form β-hydroxy aldehydes (aldol) or β-hydroxy ketones (ketol) respectively. This reaction is known as aldol condensation. Explain the mechanism of Aldol condensation. Aldol condensation is an organic reaction in which an… Continue reading FAQs

It is important to differentiate aldol condensation from various reactions of carbonyl compounds. In a case of Perkin reaction, enolate generated by anhydride is aromatic. A Claisen condensation contains two ester compounds. A Henry reaction contains an aliphatic nitro compound and an aldehyde. Dieckmann condensation contains 2 ester groups present in the same molecule, which produces cyclic… Continue reading Types of Condensation

Reaction between Benzaldehyde and Acetophenone: The reaction between benzaldehyde and acetophenone undergo cross aldol condensation in presence of dil. NaOH.  In this reaction benzaldehyde have no alpha hydrogen but acetophenone have alpha hydrogen so its undergo aldol condensation form β-hydroxy ketone.  Furthermore, dehydration leads to the formation of the α, β – unsaturated ketone.

The condensation reaction between two different molecules of an aldehyde or ketone in a protic solvent such as water or alcohol constitutes the crossed aldol reaction. When condensation is between two different carbonyl compounds, it is called crossed aldol condensation. When both aldehydes have alpha hydrogens, both can form carbanions and can also act as carbanion acceptors.… Continue reading Crossed Aldol Condensation

Step-1: In reverse order, The hydroxide ion deprotonates the aldehyde. Step-2: Here Enolate ion 1 adds to the unreacted aldehyde. Step-3: Alkoxide ion 2 is protonated by water. Step-4: A small amount of aldol is converted into enolate ion (4) by hydroxide ion. Step-5: Here Enolate Ion(4) loses a hydroxide ion. Step 1 to step… Continue reading Mechanism of Aldol Condensation

Aldol Condensation can be defined as an organic reaction in which enolate ion reacts with a carbonyl compound to form β-hydroxy ketone or β-hydroxy aldehyde, followed by dehydration to give a conjugated enone. Aldol Condensation plays a vital role in organic synthesis, creating a path to form carbon-carbon bonds. The general reaction of aldol condensation is General Aldol… Continue reading Aldol Condensation Reaction

What is Aldol Condensation? Aldol condensation occurs in aldehydes having α-hydrogen with a dilute base to give β-hydroxy aldehydes called aldols. This reaction is most commonly known as aldol condensation. If the condensation reaction occurs between two different carbonyl compounds it is called crossed aldol condensation.